United States was the largest outside supplier.
What this market covers
Complete treatment installations with an accelerator, beam delivery and patient positioning. Buyers are cancer centres building dedicated treatment suites.
Typical segments
- Cyclotron based systems
- Synchrotron based systems
- Single room compact systems
- Treatment planning software
Source: Eurostat
Why this market is moving now
- Extra-EU import value rose 50% from 2020 to 2025, a direct read on EU demand for sourced supply.
- Supply is concentrated: one country provided a large share of extra-EU imports in 2025.
Key figures
Each figure names the source it came from. Open the source list below to read the quoted line.
| Figure | Value | Year | Source |
|---|---|---|---|
| The EU imported €28.8 million of products under CN code 85431000 (Electrical particle accelerators for electrons, protons, etc.) from outside the EU in 2025. | 28.8 EUR million | 2025 | Eurostat |
| Extra-EU imports of CN 85431000 were up 50% in 2025 compared with 2020 (€19.2 million), calculated from Eurostat values. | +50 % since 2020 | 2025 | Eurostat |
| EU exports of CN 85431000 to countries outside the EU were worth €86.4 million in 2025. | 86.4 EUR million | 2025 | Eurostat |
| Trade between EU member states in CN 85431000 (intra-EU arrivals) came to €53.3 million in 2025. | 53.3 EUR million | 2025 | Eurostat |
| United States was the largest non-EU supplier of CN 85431000 to the EU in 2025, with €8.3 million, or 29% of extra-EU imports. | 8.3 EUR million | 2025 | Eurostat |
| EU exports of CN 85431000 to the United States were €28.7 million in 2025. | 28.7 EUR million | 2025 | Eurostat |
| The average value of extra-EU imports of CN 85431000 was €131.15 per kilogram in 2025, calculated from Eurostat value and weight. | 131.15 EUR per kg | 2025 | Eurostat |
| Belgium was the largest EU exporter of CN 85431000 to non-EU countries in 2025, at €52.1 million. | 52.1 EUR million | 2025 | Eurostat |
| The EU had 1,791 enterprises in NACE class C2660 (Manufacture of irradiation, electromedical and electrotherapeutic equipment) in 2023. | 1,791 enterprises | 2023 | Eurostat |
| EU enterprises in NACE class C2660 had net turnover of €30.54 billion in 2023. | 30.54 EUR billion | 2023 | Eurostat |
| NACE class C2660 employed 74,126 people across the EU in 2021. | 74,126 persons employed | 2021 | Eurostat |
| The US had 2,220 private establishments in NAICS 334510 (Electromedical and electrotherapeutic apparatus manufacturing) in 2025. | 2,220 establishments | 2025 | U.S. Bureau of Labor Statistics |
| NAICS 334510 employed an average of 72,575 people in US private industry in 2025. | 72,575 jobs | 2025 | U.S. Bureau of Labor Statistics |
| US employment in NAICS 334510 changed by -1% between 2020 (73,147 jobs) and 2025, calculated from BLS figures. | -1 % since 2020 | 2025 | U.S. Bureau of Labor Statistics |
| Average annual pay in US NAICS 334510 was $140,429 in 2025. | 140,429 USD per year | 2025 | U.S. Bureau of Labor Statistics |
| The FDA has recorded 5 510(k) clearances for devices named "proton beam therapy system". | 5 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| 1 of those clearances were issued from 2021 to 2025. | 1 510(k) clearances | 2025 | U.S. Food and Drug Administration |
| Hitachi , Ltd. holds 1 510(k) clearances for devices named "proton beam therapy system". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Loma Linda University Medical Center holds 1 510(k) clearances for devices named "proton beam therapy system". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Optivus Technology, Inc. holds 1 510(k) clearances for devices named "proton beam therapy system". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| P-Cure, Ltd. holds 1 510(k) clearances for devices named "proton beam therapy system". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Protom International Holding Corporation holds 1 510(k) clearances for devices named "proton beam therapy system". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| PubMed indexed 717 papers mentioning "proton therapy" in the title or abstract in 2025. | 717 papers | 2025 | U.S. National Library of Medicine |
Sources and method
The figures on this page come from the public sources listed below. Read how we work.
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
Quoted lines
- Figure 1
DS-045409, reporter EU27_2020, product 85431000, partner EXT_EU27_2020, flow import, 2025, VALUE_IN_EUROS 28805745
- Figure 2
DS-045409, reporter EU27_2020, product 85431000, flow import, 2020 VALUE_IN_EUROS 19166785; 2025 VALUE_IN_EUROS 28805745
- Figure 3
DS-045409, reporter EU27_2020, product 85431000, partner EXT_EU27_2020, flow export, 2025, VALUE_IN_EUROS 86432031
- Figure 4
DS-045409, reporter EU27_2020, product 85431000, partner INT_EU27_2020, flow import, 2025, VALUE_IN_EUROS 53349828
- Figure 5
DS-045409, reporter EU27_2020, product 85431000, partner US, flow import, 2025, VALUE_IN_EUROS 8328799
- Figure 6
DS-045409, reporter EU27_2020, product 85431000, partner US, flow export, 2025, VALUE_IN_EUROS 28726498
- Figure 7
DS-045409, reporter EU27_2020, product 85431000, flow import, 2025, VALUE_IN_EUROS 28805745, QUANTITY_IN_100KG 2196
- Figure 1
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
Quoted lines
- Figure 8
DS-045409, reporter BE, product 85431000, partner EXT_EU27_2020, flow export, 2025, VALUE_IN_EUROS 52059981
- Figure 8
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
Quoted lines
- Figure 9
sbs_ovw_act, geo EU27_2020, nace_r2 C2660, indic_sbs ENT_NR, 2023, 1791
- Figure 10
sbs_ovw_act, geo EU27_2020, nace_r2 C2660, indic_sbs NETTUR_MEUR, 2023, 30540
- Figure 11
sbs_ovw_act, geo EU27_2020, nace_r2 C2660, indic_sbs EMP_NR, 2021, 74126
- Figure 9
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 334510, 2025 (2026-11-04)
Quoted lines
- Figure 12
QCEW 2025 annual, US000, private, NAICS 334510, annual_avg_estabs 2220
- Figure 13
QCEW 2025 annual, US000, private, NAICS 334510, annual_avg_emplvl 72575
- Figure 14
QCEW 2020 annual_avg_emplvl 73147; 2025 annual_avg_emplvl 72575
- Figure 15
QCEW 2025 annual, US000, private, NAICS 334510, avg_annual_pay 140429
- Figure 12
- U.S. Food and Drug Administration: openFDA 510(k) clearances, device_name "proton beam therapy system" (2026-11-04)
Quoted lines
- Figure 16
openFDA device/510k device_name:"proton beam therapy system", sum of counts by decision_date = 5
- Figure 17
openFDA device/510k decision_date 2021-2025 count = 1
- Figure 16
- U.S. Food and Drug Administration: openFDA 510(k) clearances by applicant, device_name "proton beam therapy system" (2026-11-04)
Quoted lines
- Figure 18
applicant.exact "Hitachi , Ltd." count 1
- Figure 19
applicant.exact "Loma Linda University Medical Center" count 1
- Figure 20
applicant.exact "Optivus Technology, Inc." count 1
- Figure 21
applicant.exact "P-Cure, Ltd." count 1
- Figure 22
applicant.exact "Protom International Holding Corporation" count 1
- Figure 18
- U.S. National Library of Medicine: PubMed search "proton therapy"[tiab] AND 2025[dp] (2026-11-04)
Quoted lines
- Figure 23
esearch count 717
- Figure 23
Buyers and suppliers
Who buys
- Cancer hospitals
- University medical centres
- Private oncology groups
Large non-EU suppliers to the EU
Companies to watch
Hitachi , Ltd.
1 FDA 510(k) clearances for devices named "proton beam therapy system".
Loma Linda University Medical Center
1 FDA 510(k) clearances for devices named "proton beam therapy system".
Optivus Technology, Inc.
1 FDA 510(k) clearances for devices named "proton beam therapy system".
P-Cure, Ltd.
1 FDA 510(k) clearances for devices named "proton beam therapy system".
Protom International Holding Corporation
1 FDA 510(k) clearances for devices named "proton beam therapy system".
What the full report covers
- 01Executive summary
The answer in one page: size, direction and what moves it - 02Market definition and scope
What is in and out of the European Union market - 03Market size, 2021 to 2025
Historical series and growth rates - 04Outlook to 2031
Base, low and high scenarios with stated assumptions - 05Rules, policy and deadlines
Regulation and programmes that change demand - 06Drivers and barriers
What accelerates or slows adoption, by customer segment - 07Prices, costs and margins
Unit economics where public data allows - 08Competitive landscape
8 to 12 company profiles with recent moves - 09Opportunities and risks
For new entrants, suppliers and investors - 10Method and sources
Every assumption and source, listed
Included with the full report
- PDF report, 40 to 60 pages
- Excel data pack
- Ready-to-use charts
- Method note and assumptions
- Written to order in 5 working days
Frequently asked questions
How big is the EU proton therapy system market?
There is no single official market total. Eurostat trade data shows the EU imported €28.8 million of goods under CN 85431000 from outside the EU in 2025 and exported €86.4 million.
Where does the EU import proton therapy system from?
United States was the largest non-EU supplier in 2025. Other large suppliers included Switzerland, Japan, Canada.
What is the average import price of proton therapy system in the EU?
Dividing Eurostat import value by weight gives about €131.15 per kilogram for CN 85431000 in 2025.
Which EU countries export the most proton therapy system?
Belgium led EU exports to non-EU countries in 2025, followed by Sweden, France.
How many proton therapy system devices are cleared by the FDA?
openFDA lists 5 510(k) clearances for devices named proton beam therapy system.
Which companies hold the most FDA clearances for proton therapy system?
By 510(k) count: Hitachi , Ltd., Loma Linda University Medical Center, Optivus Technology, Inc., P-Cure, Ltd..
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