What this market covers
Biologic or synthetic scaffolds that support tissue regrowth in chronic and surgical wounds while limiting infection. Buyers are hospitals, wound care centres and surgeons.
Typical segments
- Collagen matrices
- Silver impregnated matrices
- Synthetic matrices
- Biologic skin substitutes
Why this market is moving now
- US employment in the core industry shifted +3% since 2020.
Key figures
Each figure names the source it came from. Open the source list below to read the quoted line.
| Figure | Value | Year | Source |
|---|---|---|---|
| The EU had 63,227 enterprises in NACE class C3250 (Manufacture of medical and dental instruments and supplies) in 2023. | 63,227 enterprises | 2023 | Eurostat |
| EU enterprises in NACE class C3250 had net turnover of €105.31 billion in 2021. | 105.31 EUR billion | 2021 | Eurostat |
| NACE class C3250 employed 600,000 people across the EU in 2023. | 600,000 persons employed | 2023 | Eurostat |
| The US had 3,528 private establishments in NAICS 339113 (Surgical appliance and supplies manufacturing) in 2025. | 3,528 establishments | 2025 | U.S. Bureau of Labor Statistics |
| NAICS 339113 employed an average of 105,116 people in US private industry in 2025. | 105,116 jobs | 2025 | U.S. Bureau of Labor Statistics |
| US employment in NAICS 339113 changed by +3% between 2020 (102,053 jobs) and 2025, calculated from BLS figures. | +3 % change | 2025 | U.S. Bureau of Labor Statistics |
| Average annual pay in US NAICS 339113 was $102,311 in 2025. | 102,311 USD per year | 2025 | U.S. Bureau of Labor Statistics |
| The FDA has recorded 369 510(k) clearances for devices named "wound dressing". | 369 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| 24 of those clearances were issued from 2021 to 2025. | 24 510(k) clearances | 2025 | U.S. Food and Drug Administration |
| Polymedica Industries, Inc. holds 10 510(k) clearances for devices named "wound dressing". | 10 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Bioderm, Inc. holds 9 510(k) clearances for devices named "wound dressing". | 9 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Acrymed, Inc. holds 8 510(k) clearances for devices named "wound dressing". | 8 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Calgon Vestal Div. holds 8 510(k) clearances for devices named "wound dressing". | 8 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Carrington Laboratories, Inc. holds 7 510(k) clearances for devices named "wound dressing". | 7 510(k) clearances | 2026 | U.S. Food and Drug Administration |
| Dermaphylyx, Inc. holds 6 510(k) clearances for devices named "wound dressing". | 6 510(k) clearances | 2026 | U.S. Food and Drug Administration |
Sources and method
The figures on this page come from the public sources listed below. Read how we work.
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
Quoted lines
- Figure 1
sbs_ovw_act, geo EU27_2020, nace_r2 C3250, indic_sbs ENT_NR, 2023, 63227
- Figure 2
sbs_ovw_act, geo EU27_2020, nace_r2 C3250, indic_sbs NETTUR_MEUR, 2021, 105308
- Figure 3
sbs_ovw_act, geo EU27_2020, nace_r2 C3250, indic_sbs EMP_NR, 2023, 600000
- Figure 1
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 339113, 2025 (2026-11-04)
Quoted lines
- Figure 4
QCEW 2025 annual, US000, private, NAICS 339113, annual_avg_estabs 3528
- Figure 5
QCEW 2025 annual, US000, private, NAICS 339113, annual_avg_emplvl 105116
- Figure 6
QCEW 2020 annual_avg_emplvl 102053; 2025 annual_avg_emplvl 105116
- Figure 7
QCEW 2025 annual, US000, private, NAICS 339113, avg_annual_pay 102311
- Figure 4
- U.S. Food and Drug Administration: openFDA 510(k) clearances, device_name "wound dressing" (2026-11-04)
Quoted lines
- Figure 8
openFDA device/510k device_name:"wound dressing", sum of counts by decision_date = 369
- Figure 9
openFDA device/510k decision_date 2021-2025 count = 24
- Figure 8
- U.S. Food and Drug Administration: openFDA 510(k) clearances by applicant, device_name "wound dressing" (2026-11-04)
Quoted lines
- Figure 10
applicant.exact "Polymedica Industries, Inc." count 10
- Figure 11
applicant.exact "Bioderm, Inc." count 9
- Figure 12
applicant.exact "Acrymed, Inc." count 8
- Figure 13
applicant.exact "Calgon Vestal Div." count 8
- Figure 14
applicant.exact "Carrington Laboratories, Inc." count 7
- Figure 15
applicant.exact "Dermaphylyx, Inc." count 6
- Figure 10
Buyers and suppliers
Who buys
- Hospitals
- Wound care centres
- Surgical practices
Companies to watch
Polymedica Industries, Inc.
10 FDA 510(k) clearances for devices named "wound dressing".
Bioderm, Inc.
9 FDA 510(k) clearances for devices named "wound dressing".
Acrymed, Inc.
8 FDA 510(k) clearances for devices named "wound dressing".
Calgon Vestal Div.
8 FDA 510(k) clearances for devices named "wound dressing".
Carrington Laboratories, Inc.
7 FDA 510(k) clearances for devices named "wound dressing".
Dermaphylyx, Inc.
6 FDA 510(k) clearances for devices named "wound dressing".
What the full report covers
- 01Executive summary
The answer in one page: size, direction and what moves it - 02Market definition and scope
What is in and out of the United States market - 03Market size, 2021 to 2025
Historical series and growth rates - 04Outlook to 2031
Base, low and high scenarios with stated assumptions - 05Rules, policy and deadlines
Regulation and programmes that change demand - 06Drivers and barriers
What accelerates or slows adoption, by customer segment - 07Prices, costs and margins
Unit economics where public data allows - 08Competitive landscape
8 to 12 company profiles with recent moves - 09Opportunities and risks
For new entrants, suppliers and investors - 10Method and sources
Every assumption and source, listed
Included with the full report
- PDF report, 40 to 60 pages
- Excel data pack
- Ready-to-use charts
- Method note and assumptions
- Written to order in 5 working days
Frequently asked questions
How many antimicrobial regenerative wound matrix devices are cleared by the FDA?
openFDA lists 369 510(k) clearances for devices named wound dressing.
Which companies hold the most FDA clearances for antimicrobial regenerative wound matrix?
By 510(k) count: Polymedica Industries, Inc., Bioderm, Inc., Acrymed, Inc., Calgon Vestal Div..
How many US companies are in the antimicrobial regenerative wound matrix industry?
BLS counts 3,528 private establishments in NAICS 339113 (Surgical appliance and supplies manufacturing), the closest official industry.
How many EU companies are in the antimicrobial regenerative wound matrix industry?
Eurostat counts 63,227 enterprises in NACE class C3250 (Manufacture of medical and dental instruments and supplies).
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